There may be soon millions of people suffering from diabetes who no longer have to pinch fingers and injecting insulin daily. Yugish Codeba, an endocrinologist from Mayo Clinic along with Dr. Ananda Bezo have developed an artificial pancreas that automatically delivers insulin custom and accurately, something so far has not been possible. In the framework of its activity, the Codeba doctors and Bezo to present recent results on the effects of the daily routine in blood glucose at a Convention of the American Association for the fight against diabetes that will be conducted this month in San Diego. The effects of physical activity on low intensity, which simulates the activity of everyday life, on par with the measurement with precision and sensors speed at different levels of glucose not been investigated in patients with type 1 diabetes, said Dr. Codeba.
One of the new findings is that basic after eating physical activity could have a big impact on blood glucose in patients who suffer from type 1 diabetes. The result It was predictable, but we wanted to know to what extent the phenomenon exists in people with type 1 diabetes?, said doctor Codeba. The level of blood sugar in diabetics who were low intensity physical activity after the meal, was similar to that of the people with full functioning of the pancreas. However, among those who were to sit down after eating, blood sugar levels rose. Researchers plan to combine results in the development of the artificial pancreas at the clinic may in a closed circuit system, which is in development and includes a mechanism of monitoring of glucose in the blood, an automatic insulin pump, a series of sensors placed in the body perform follow-up activity, and a central processing unit.
The artificial pancreas clinical trials should begin in November in some hospitalized patients. Participants in the research shall maintain a strict diet of eating and exercise, and a regime of administration of insulin of the unit of clinical trials in May. Data shall be entered in an algorithm for the supply of insulin that mimics the natural process in the body for the monitoring of glucose in the blood and the ratio of an adequate response. Physical activity increases the action of insulin, which reduces the concentration of glucose in the blood, said Dr. Codeba. The real-time detection of physical activity and sample of the effect on glucose Dynamics play a vital role in the design of automatic insulin delivery system.. Dr. Codeba and other researchers at the clinic may, spent 15 years working on various aspects of diabetes and obesity. They are cooperating in the development of the artificial pancreas, and the development of an algorithm that gives peace of mind to patients and save the daily routine of diabetes care. Dr. Bezo, presenting results according to which the level of sugar in the blood of healthy adults further decreases quickly in the morning than at dinner, a phenomenon that represents a daily pattern in relation to the natural action of insulin. It offers to investigate this phenomenon further and perhaps incorporate it in an algorithm that is running in the closed circle. The research was funded by grants from national institutes.